The Catalans are overwhelming favourites to win the game and have an outstanding home record in the Champions League, remaining unbeaten at the Nou Camp in the competition since losing to Bayern Munich in 2013.
Barcelona waited and gave an apt reply to not only AC Milan, but also their critics.
A summary of Sunday's action in Serie A and Bundesliga.
Manchester City's quadruple bid remained intact as Ilkay Gundogan and Kevin de Bruyne secured a 2-0 win at Everton in their FA Cup quarter-final clash
AC Milan have been left dwelling on the past as they prepare to host Barcelona in a Champions League last-16 first leg tie on Wednesday when Lionel Messi will try to score for the Catalans for the 15th match in a row.
Lionel Messi fired Barcelona into the last 16 of the Champions League with two goals in their 3-0 victory at Spartak Moscow on Tuesday but holders Chelsea are walking a tightrope after a crushing defeat by Juventus.
In the women's section being held simultaneously, the Indians came back strongly to beat Poland 3-1 aided by victories from D Harika and Tania Sachdev on board two and three. Its surprising that Tania Sachdev was rested in the previous round when the Indian team drew with Serbia, losing on last two boards.
Barcelona are suing Neymar for 8.5 million euros for alleged breach of contract and demanding he return the loyalty bonus paid after he renewed his deal in October, less than a year before he signed for Paris St. Germain, the club said Tuesday.
Barcelona's early season form has been on a par with their habitually high standards but as they prepare to visit Celtic in the Champions League there remains a question mark hanging over their makeshift defence.
The Catalans will not just be looking to extend their domestic hegemony, though, as they have spent a combined 250 million euros ($280 million) on a renewed bid to win the Champions League.
Barca's Suarez in firing line after European away goals drought
Moreno, who holds a degree from the University of Barcelona in trade and international relations, began working alongside Luis Enrique with Barcelona's B team in 2010 in the scouting department.
Lionel Messi was at the top of his game as Barcelona earned a 3-2 win at Athletic Bilbao on Wednesday to move up to third in La Liga.
As we near the end of another eventful year, 15 top moments from the world of arts and culture.
The millions of fans around the globe who will tune in to watch Sunday's 'Clasico' in Barcelona could witness the death throes of Real Madrid's La Liga title challenge in their seventh match of the season. Defeat at the Nou Camp for Jose Mourinho's side, who are chasing a second consecutive title after ending Barca's three-year run as champions, would stretch the Catalan club's lead over their bitter rivals to 11 points.
Barcelona coach Luis Enrique has ended uncertainty over his future by agreeing a one-year contract extension with the Spanish and European champions until the end of the 2016-17 season.
'He's an exceptional talent, him and Cristiano have been the best players in the world the last decade and he showed why we think that and why this team have won the Champions League so many times'
Sevilla midfielder Aleix Vidal will join treble winners Barcelona.
Images from La Liga matches played on Sunday
De Jong is proud to join the likes of compatriots Ronald Koeman, Frank de Boer and Patrick Kluivert in heading to the Nou Camp, having dreamed of wearing Barca colours.
Lionel Messi scored his 12th league goal of the season but Barcelona had to rely on exceptional saves from Marc-Andre ter Stegen as they rode their luck to win 2-0 at Athletic Bilbao on Saturday and stay four points clear at the top of La Liga.
Joaquin, 37, became the oldest scorer in a Seville top-flight derby when he rose to head home at the near post in the 79th minute, shortly after the visitors had had midfielder Roque Mesa sent off for two bookings.
Bayern Munich manager Pep Guardiola has termed his former club Barcelona as the 'best team in the world', after both the teams were being drawn against each other for the high-octane Champions League semi-final clash.
A round-up of all football-related news...
Arsenal extend Aubameyang stay with new three-year deal
Ronaldinho has not played a competitive match since 2015 but had avoided calling a definitive halt to his career until now.
Images from the La Liga match played between FC Barcelona and Sevilla on at Camp Nou on Sunday
Barcelona president Josep Maria Bartomeu has reassured his club's supporters that Lionel Messi's new contract has been signed, albeit by the player's father.
Santiago Solari got off to the perfect start as Real Madrid's interim coach when his side thrashed Melilla 4-0 in the Copa del Rey on Wednesday.
Lionel Messi led Barcelona to a 3-1 win at home to Napoli for a 4-2 aggregate victory which took the club into the Champions League quarter-finals, where they face Bayern Munich.
Atletico Madrid earned a 1-1 draw away to Girona in a chaotic and entertaining Copa del Rey last 16 first-leg match on Wednesday, leaving the tie finely balanced.
Barcelona defender Eric Abidal is to have a liver transplant, the Spanish and European champions said on Thursday.
Real Madrid claimed their first Spanish Super Cup in four years and a morale-boosting success against their arch-rivals when Gonzalo Higuain and Cristiano Ronaldo struck in a 2-1 win against 10-man Barcelona on Wednesday.
The clinical Argentine Messi now has 11 goals in his last five games in all competitions and with record signing Ousmane Dembele injured and Luis Suarez rested, he put on a sensational show at Camp Nou to extend Barcelona's La Liga lead.
Rediff.com gives you a glimpse of the jubilant Catalan team...
The victory takes Barcelona up to fourth with 10 points after six games, one point behind surprise leaders Granada, Athletic Bilbao, who visit Leganes on Wednesday, and Real Madrid ahead of their game at home to Osasuna the same night.
Cesc Fabregas has finally signed for Barcelona on a five-year deal.
The Catalans have kept five clean sheets in their last six games, which bodes well for their title run in.
'They were better than us for some spells and we know what awaits us over there' Valverde pointed to his team's sensational exit from last year's competition to AS Roma after a 4-1 cushion from the first leg and said they would be taking nothing for granted in Tuesday's return game at Anfield.